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If your budget is zero, these alternatives match many features of ChemDraw 15.0: Trials are generally offered for the current version (e

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| Software | Platform | Key Strengths | |----------|----------|----------------| | | Windows, Mac (wine) | Freeware, IUPAC naming, 2D drawing, good export options. | | MarvinSketch (ChemAxon) | Win, Mac, Linux, Web | Very powerful, predicts pKa/logP, free for academic use. | | KingDraw | Win, Mac, Android, iOS | Modern interface, cloud sync, completely free. | | Biovia Draw (Dassault) | Windows | Formerly ISIS/Draw, basic but reliable. | | XDrawChem | Linux, Mac, Windows | Open-source, simple, fast. |