Depending on whether you want to keep using the Adobe PDF features in Office or simply stop the error message, you can take the following steps: Article - Run-time Error 53 or 4707 -... - ser
The /Library/Application Support/Adobe/ directory (system-wide, not user-specific) houses shared resources used by all Adobe applications. Inside: Depending on whether you want to keep using
You updated macOS or Microsoft Office, rendering older versions of the Adobe plugin incompatible. Depending on whether you want to keep using
You removed Adobe Acrobat, but the Office add-in files remained behind. Depending on whether you want to keep using
, which occurs when a Microsoft Office application attempts to call the Adobe framework but cannot find or properly execute it. Microsoft Learn