This is a little-known fact: IE 5.0 SP2 didn't have a native pop-up blocker, but it introduced the mechanisms for third-party toolbars (the precursors to the Google Toolbar) to work securely. The Service Pack stabilized the API. Without SP2's BHO improvements, the era of toolbar customization might have never taken off.
Do you have a memory of developing for or using IE 5.0 SP2? Share it in the comments below (but probably not on a machine running IE 5.0 SP2).
As the web became more commercial, SP2 addressed numerous "buffer overflow" vulnerabilities and improved the handling of digital certificates and SSL encryption. The Windows Integration and Controversy