On Apple Silicon (M1/M2/M3) Macs, tools like (based on Wine) or Parallels Desktop can run the Windows version. Performance varies:
Since there is no native Mac installer, you must acquire the Windows version from a digital storefront: Mortal Kombat - App Store
The game costs as little as . Given the effort to run it on a Mac, saving $5 is not worth the risk.
Feral Interactive and Warner Bros. have confirmed no plans to release a 64-bit update or a remastered version for Apple Silicon.